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Meningococcal Factor H Binding Protein fHbpd184 Polymorphism Influences Clinical Course of Meningococcal Meningitis
Factor H Binding protein (fHbp) is an important meningococcal virulence factor, enabling the meningococcus to evade the complement system, and a main target for vaccination. Recently, the structure of fHBP complexed with factor H (fH) was published. Two fHbp glutamic acids, E(283) and E(304), form s...
Autores principales: | Piet, Jurgen R., Brouwer, Matthijs C., Exley, Rachel, van der Veen, Stijn, van de Beek, Diederik, van der Ende, Arie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479137/ https://www.ncbi.nlm.nih.gov/pubmed/23110143 http://dx.doi.org/10.1371/journal.pone.0047973 |
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