DNA of a circular minichromosome linearized by restriction enzymes or other reagents is resistant to further cleavage: an influence of chromatin topology on the accessibility of DNA

The accessibility of DNA in chromatin is an essential factor in regulating its activities. We studied the accessibility of the DNA in a ∼170 kb circular minichromosome to DNA-cleaving reagents using pulsed-field gel electrophoresis and fibre-fluorescence in situ hybridization on combed DNA molecules...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumala, Sławomir, Hadj-Sahraoui, Yasmina, Rzeszowska-Wolny, Joanna, Hancock, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479189/
https://www.ncbi.nlm.nih.gov/pubmed/22848103
http://dx.doi.org/10.1093/nar/gks723

Ejemplares similares

Ejemplares similares