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Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity

Polyuridylation is emerging as a ubiquitous post-translational modification with important roles in multiple aspects of RNA metabolism. These poly (U) tails are added by poly (U) polymerases with homology to poly (A) polymerases; nevertheless, the selection for UTP over ATP remains enigmatic. We rep...

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Detalles Bibliográficos
Autores principales:	Lunde, Bradley M., Magler, Iris, Meinhart, Anton
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479196/ https://www.ncbi.nlm.nih.gov/pubmed/22885303 http://dx.doi.org/10.1093/nar/gks740

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