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Gastric Emptying in Migraine: A Comparison With Functional Dyspepsia

BACKGROUND/AIMS: Gastric stasis in migraineurs remains controversial. The aim of this study is to investigate gastric emptying (GE) time, and any associations between GE parameters and dyspeptic symptoms among patients with functional dyspepsia (FD) and migraine without any gastrointestinal symptoms...

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Autores principales: Yu, Yeon Hwa, Jo, Yunju, Jung, Jun Young, Kim, Byung Kun, Seok, Ju Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Neurogastroenterology and Motility 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479255/
https://www.ncbi.nlm.nih.gov/pubmed/23106002
http://dx.doi.org/10.5056/jnm.2012.18.4.412
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author Yu, Yeon Hwa
Jo, Yunju
Jung, Jun Young
Kim, Byung Kun
Seok, Ju Won
author_facet Yu, Yeon Hwa
Jo, Yunju
Jung, Jun Young
Kim, Byung Kun
Seok, Ju Won
author_sort Yu, Yeon Hwa
collection PubMed
description BACKGROUND/AIMS: Gastric stasis in migraineurs remains controversial. The aim of this study is to investigate gastric emptying (GE) time, and any associations between GE parameters and dyspeptic symptoms among patients with functional dyspepsia (FD) and migraine without any gastrointestinal symptoms during the interictal period. METHODS: We enrolled 27 migraine patients, 32 FD patients and 12 healthy people as controls, and performed GE scintigraphy as gastric function test. Gastrointestinal symptoms were evaluated in the FD and migraine. RESULTS: The age-adjusted mean gastric half-emptying time in FD (125.51 ± 52.55 minutes) patients was longer than in migraineurs (100.82 ± 23.94 minutes, P = 0.035) and controls (95.25 ± 23.29 minutes, P = 0.021). The percentage of gastric retention was higher in FD than in migraine. However, migraineurs did not show an obvious delayed gastric emptying or an increase of gastric retention when compared to the normal controls. The association between each dyspeptic symptom and GE parameters was not significant, but postprandial fullness and early satiety showed a tendency of delayed GE. In migraineurs, GE time did not show significant association with nausea and vomiting during interictal periods. CONCLUSIONS: Delayed GE does not appear to be a mechanism that patients with FD and migraine have in common. Migraineurs without dyspepsia during interictal period had normal GE, and further study for association with FD should be investigated.
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spelling pubmed-34792552012-10-26 Gastric Emptying in Migraine: A Comparison With Functional Dyspepsia Yu, Yeon Hwa Jo, Yunju Jung, Jun Young Kim, Byung Kun Seok, Ju Won J Neurogastroenterol Motil Original Article BACKGROUND/AIMS: Gastric stasis in migraineurs remains controversial. The aim of this study is to investigate gastric emptying (GE) time, and any associations between GE parameters and dyspeptic symptoms among patients with functional dyspepsia (FD) and migraine without any gastrointestinal symptoms during the interictal period. METHODS: We enrolled 27 migraine patients, 32 FD patients and 12 healthy people as controls, and performed GE scintigraphy as gastric function test. Gastrointestinal symptoms were evaluated in the FD and migraine. RESULTS: The age-adjusted mean gastric half-emptying time in FD (125.51 ± 52.55 minutes) patients was longer than in migraineurs (100.82 ± 23.94 minutes, P = 0.035) and controls (95.25 ± 23.29 minutes, P = 0.021). The percentage of gastric retention was higher in FD than in migraine. However, migraineurs did not show an obvious delayed gastric emptying or an increase of gastric retention when compared to the normal controls. The association between each dyspeptic symptom and GE parameters was not significant, but postprandial fullness and early satiety showed a tendency of delayed GE. In migraineurs, GE time did not show significant association with nausea and vomiting during interictal periods. CONCLUSIONS: Delayed GE does not appear to be a mechanism that patients with FD and migraine have in common. Migraineurs without dyspepsia during interictal period had normal GE, and further study for association with FD should be investigated. Korean Society of Neurogastroenterology and Motility 2012-10 2012-10-09 /pmc/articles/PMC3479255/ /pubmed/23106002 http://dx.doi.org/10.5056/jnm.2012.18.4.412 Text en © 2012 The Korean Society of Neurogastroenterology and Motility http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Yu, Yeon Hwa
Jo, Yunju
Jung, Jun Young
Kim, Byung Kun
Seok, Ju Won
Gastric Emptying in Migraine: A Comparison With Functional Dyspepsia
title Gastric Emptying in Migraine: A Comparison With Functional Dyspepsia
title_full Gastric Emptying in Migraine: A Comparison With Functional Dyspepsia
title_fullStr Gastric Emptying in Migraine: A Comparison With Functional Dyspepsia
title_full_unstemmed Gastric Emptying in Migraine: A Comparison With Functional Dyspepsia
title_short Gastric Emptying in Migraine: A Comparison With Functional Dyspepsia
title_sort gastric emptying in migraine: a comparison with functional dyspepsia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479255/
https://www.ncbi.nlm.nih.gov/pubmed/23106002
http://dx.doi.org/10.5056/jnm.2012.18.4.412
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