DRD2 and PPP1R1B (DARPP-32) polymorphisms independently confer increased risk for autism spectrum disorders and additively predict affected status in male-only affected sib-pair families

BACKGROUND: The neurotransmitter dopamine (DA) modulates executive functions, learning, and emotional processing, all of which are impaired in individuals with autism spectrum disorders (ASDs). Our previous findings suggest a role for dopamine-related genes in families with only affected males. METH...

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Detalles Bibliográficos
Autores principales: Hettinger, Joe A, Liu, Xudong, Hudson, Melissa L, Lee, Alana, Cohen, Ira L, Michaelis, Ron C, Schwartz, Charles E, Lewis, Suzanne ME, Holden, Jeanette JA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479424/
https://www.ncbi.nlm.nih.gov/pubmed/22559203
http://dx.doi.org/10.1186/1744-9081-8-19

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