Cargando…
Pathogenesis of and strategies for preventing Edwardsiella tarda infection in fish
Edwardsiella tarda is one of the serious fish pathogens, infecting both cultured and wild fish species. Research on edwardsiellosis has revealed that E. tarda has a broad host range and geographic distribution, and contains important virulence factors that enhance bacterial survival and pathogenesis...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479428/ https://www.ncbi.nlm.nih.gov/pubmed/23035843 http://dx.doi.org/10.1186/1297-9716-43-67 |
_version_ | 1782247447840423936 |
---|---|
author | Park, Seong Bin Aoki, Takashi Jung, Tae Sung |
author_facet | Park, Seong Bin Aoki, Takashi Jung, Tae Sung |
author_sort | Park, Seong Bin |
collection | PubMed |
description | Edwardsiella tarda is one of the serious fish pathogens, infecting both cultured and wild fish species. Research on edwardsiellosis has revealed that E. tarda has a broad host range and geographic distribution, and contains important virulence factors that enhance bacterial survival and pathogenesis in hosts. Although recent progress in edwardsiellosis research has enabled the development of numerous, highly effective vaccine candidates, these efforts have not been translated into a commercialized vaccine. The present review aims to provide an overview of the identification, pathology, diagnosis and virulence factors of E. tarda in fish, and describe recent strategies for developing vaccines against edwardsiellosis. The hope is that this presentation will be useful not only from the standpoint of understanding the pathogenesis of E. tarda, but also from the perspective of facilitating the development of effective vaccines. |
format | Online Article Text |
id | pubmed-3479428 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-34794282012-10-24 Pathogenesis of and strategies for preventing Edwardsiella tarda infection in fish Park, Seong Bin Aoki, Takashi Jung, Tae Sung Vet Res Review Edwardsiella tarda is one of the serious fish pathogens, infecting both cultured and wild fish species. Research on edwardsiellosis has revealed that E. tarda has a broad host range and geographic distribution, and contains important virulence factors that enhance bacterial survival and pathogenesis in hosts. Although recent progress in edwardsiellosis research has enabled the development of numerous, highly effective vaccine candidates, these efforts have not been translated into a commercialized vaccine. The present review aims to provide an overview of the identification, pathology, diagnosis and virulence factors of E. tarda in fish, and describe recent strategies for developing vaccines against edwardsiellosis. The hope is that this presentation will be useful not only from the standpoint of understanding the pathogenesis of E. tarda, but also from the perspective of facilitating the development of effective vaccines. BioMed Central 2012 2012-10-04 /pmc/articles/PMC3479428/ /pubmed/23035843 http://dx.doi.org/10.1186/1297-9716-43-67 Text en Copyright ©2012 Park et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Park, Seong Bin Aoki, Takashi Jung, Tae Sung Pathogenesis of and strategies for preventing Edwardsiella tarda infection in fish |
title | Pathogenesis of and strategies for preventing Edwardsiella tarda infection in fish |
title_full | Pathogenesis of and strategies for preventing Edwardsiella tarda infection in fish |
title_fullStr | Pathogenesis of and strategies for preventing Edwardsiella tarda infection in fish |
title_full_unstemmed | Pathogenesis of and strategies for preventing Edwardsiella tarda infection in fish |
title_short | Pathogenesis of and strategies for preventing Edwardsiella tarda infection in fish |
title_sort | pathogenesis of and strategies for preventing edwardsiella tarda infection in fish |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479428/ https://www.ncbi.nlm.nih.gov/pubmed/23035843 http://dx.doi.org/10.1186/1297-9716-43-67 |
work_keys_str_mv | AT parkseongbin pathogenesisofandstrategiesforpreventingedwardsiellatardainfectioninfish AT aokitakashi pathogenesisofandstrategiesforpreventingedwardsiellatardainfectioninfish AT jungtaesung pathogenesisofandstrategiesforpreventingedwardsiellatardainfectioninfish |