Detection of BRAF(V600E) Mutations in Papillary Thyroid Carcinomas by Peptide Nucleic Acid Clamp Real-Time PCR: A Comparison with Direct Sequencing

BACKGROUND: Papillary thyroid carcinoma (PTC) of the thyroid is the most common endocrine malignancy. High prevalence of an activating point mutation of BRAF gene, BRAF(V600E), has been reported in PTC. We assessed the efficiency of peptide nucleic acid clamp real-time polymerase chain reaction (PNA...

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Detalles Bibliográficos
Autores principales: Jeong, Dongjun, Jeong, Yujun, Lee, Sungche, Lee, Hyeran, Lee, Wanju, Kim, Hyungjoo, Park, Doosan, Park, Soyoung, Mu, Wenxia, Cho, Hyun-Deuk, Oh, Mee-Hye, Lee, Sung Soo, Yang, Seung-Ha, Kim, Chang-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pathologists and The Korean Society for Cytopathology 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479705/
https://www.ncbi.nlm.nih.gov/pubmed/23109980
http://dx.doi.org/10.4132/KoreanJPathol.2012.46.1.61

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