Cargando…

Primary Pulmonary Myxoid Liposarcoma with Translocation t(12;16)(q13;p11) in a Young Female Patient: A Brief Case Report

Primary liposarcoma of the lung is an extremely rare disease. To date, only 14 cases have been reported in the literature. We experienced a case of myxoid liposarcoma of the lung treated by surgery. The tumor was well-defined, solid, lobulated mass measuring 3.5×2 cm, involving the bronchus of the l...

Descripción completa

Detalles Bibliográficos
Autores principales: Son, Choonhee, Choi, Phil Jo, Roh, Mee Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pathologists and The Korean Society for Cytopathology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479818/
https://www.ncbi.nlm.nih.gov/pubmed/23110035
http://dx.doi.org/10.4132/KoreanJPathol.2012.46.4.392
_version_ 1782247466402316288
author Son, Choonhee
Choi, Phil Jo
Roh, Mee Sook
author_facet Son, Choonhee
Choi, Phil Jo
Roh, Mee Sook
author_sort Son, Choonhee
collection PubMed
description Primary liposarcoma of the lung is an extremely rare disease. To date, only 14 cases have been reported in the literature. We experienced a case of myxoid liposarcoma of the lung treated by surgery. The tumor was well-defined, solid, lobulated mass measuring 3.5×2 cm, involving the bronchus of the left lower lobe. Microscopically, myxoid liposarcoma was identified. The fluorescence in situ hybridization confirmed the presence of a reciprocal translocation involving DNA damage-inducible transcript 3 (DDIT3) and fused in sarcoma (FUS) genes. The patient is still alive with no recurrence or metastasis at the time of writing this report (on 20 months postoperatively). To our knowledge, this is the first cytogenetic case report of pulmonary myxoid liposarcoma.
format Online
Article
Text
id pubmed-3479818
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher The Korean Society of Pathologists and The Korean Society for Cytopathology
record_format MEDLINE/PubMed
spelling pubmed-34798182012-10-29 Primary Pulmonary Myxoid Liposarcoma with Translocation t(12;16)(q13;p11) in a Young Female Patient: A Brief Case Report Son, Choonhee Choi, Phil Jo Roh, Mee Sook Korean J Pathol Case Report Primary liposarcoma of the lung is an extremely rare disease. To date, only 14 cases have been reported in the literature. We experienced a case of myxoid liposarcoma of the lung treated by surgery. The tumor was well-defined, solid, lobulated mass measuring 3.5×2 cm, involving the bronchus of the left lower lobe. Microscopically, myxoid liposarcoma was identified. The fluorescence in situ hybridization confirmed the presence of a reciprocal translocation involving DNA damage-inducible transcript 3 (DDIT3) and fused in sarcoma (FUS) genes. The patient is still alive with no recurrence or metastasis at the time of writing this report (on 20 months postoperatively). To our knowledge, this is the first cytogenetic case report of pulmonary myxoid liposarcoma. The Korean Society of Pathologists and The Korean Society for Cytopathology 2012-08 2012-08-23 /pmc/articles/PMC3479818/ /pubmed/23110035 http://dx.doi.org/10.4132/KoreanJPathol.2012.46.4.392 Text en © 2012 The Korean Society of Pathologists/The Korean Society for Cytopathology http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Son, Choonhee
Choi, Phil Jo
Roh, Mee Sook
Primary Pulmonary Myxoid Liposarcoma with Translocation t(12;16)(q13;p11) in a Young Female Patient: A Brief Case Report
title Primary Pulmonary Myxoid Liposarcoma with Translocation t(12;16)(q13;p11) in a Young Female Patient: A Brief Case Report
title_full Primary Pulmonary Myxoid Liposarcoma with Translocation t(12;16)(q13;p11) in a Young Female Patient: A Brief Case Report
title_fullStr Primary Pulmonary Myxoid Liposarcoma with Translocation t(12;16)(q13;p11) in a Young Female Patient: A Brief Case Report
title_full_unstemmed Primary Pulmonary Myxoid Liposarcoma with Translocation t(12;16)(q13;p11) in a Young Female Patient: A Brief Case Report
title_short Primary Pulmonary Myxoid Liposarcoma with Translocation t(12;16)(q13;p11) in a Young Female Patient: A Brief Case Report
title_sort primary pulmonary myxoid liposarcoma with translocation t(12;16)(q13;p11) in a young female patient: a brief case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479818/
https://www.ncbi.nlm.nih.gov/pubmed/23110035
http://dx.doi.org/10.4132/KoreanJPathol.2012.46.4.392
work_keys_str_mv AT sonchoonhee primarypulmonarymyxoidliposarcomawithtranslocationt1216q13p11inayoungfemalepatientabriefcasereport
AT choiphiljo primarypulmonarymyxoidliposarcomawithtranslocationt1216q13p11inayoungfemalepatientabriefcasereport
AT rohmeesook primarypulmonarymyxoidliposarcomawithtranslocationt1216q13p11inayoungfemalepatientabriefcasereport