Tumour angiogenesis is reduced in the Tc1 mouse model of Down Syndrome

Down Syndrome (DS) is a genetic disorder caused by full or partial trisomy of chromosome 21. It occurs in approximately 1/750 live births and presents with many clinical phenotypes including a reduced incidence of solid tumours(1,2). Recent work using the Ts65Dn model of DS, that has orthologs of ap...

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Detalles Bibliográficos
Autores principales: Reynolds, Louise E., Watson, Alan R., Baker, Marianne, Jones, Tania A., D’Amico, Gabriela, Robinson, Stephen D., Joffre, Carine, Garrido-Urbani, Sarah, Rodriguez-Manzaneque, Juan Carlos, Martino-Echarri, Estefanía, Aurrand-Lions, Michel, Sheer, Denise, Dagna-Bricarelli, Franca, Nizetic, Dean, McCabe, Christopher J., Turnell, Andrew S., Kermorgant, Stephanie, Imhof, Beat A., Adams, Ralf, Fisher, Elizabeth M.C., Tybulewicz, Victor L. J., Hart, Ian R., Hodivala-Dilke, Kairbaan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479956/
https://www.ncbi.nlm.nih.gov/pubmed/20535211
http://dx.doi.org/10.1038/nature09106

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