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Residual Tumor Cells That Drive Disease Relapse after Chemotherapy Do Not Have Enhanced Tumor Initiating Capacity

Although chemotherapy is used to treat most advanced solid tumors, recurrent disease is still the major cause of cancer-related mortality. Cancer stem cells (CSCs) have been the focus of intense research in recent years because they provide a possible explanation for disease relapse. However, the pr...

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Detalles Bibliográficos
Autores principales: Hegde, Ganapati V., de la Cruz, Cecile, Eastham-Anderson, Jeffrey, Zheng, Yanyan, Sweet-Cordero, E. Alejandro, Jackson, Erica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480356/
https://www.ncbi.nlm.nih.gov/pubmed/23115623
http://dx.doi.org/10.1371/journal.pone.0045647