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ATF6alpha Promotes Astroglial Activation and Neuronal Survival in a Chronic Mouse Model of Parkinson’s Disease
Accumulating evidence suggests a crucial role for the unfolded protein response (UPR) in Parkinson’s disease (PD). In this study, we investigated the relevance of the UPR in a mouse model of chronic MPTP/probenecid (MPTP/P) injection, which causes severe and persistent degeneration of dopaminergic n...
Autores principales: | Hashida, Koji, Kitao, Yasuko, Sudo, Hirofumi, Awa, Yoshitaka, Maeda, Shinichiro, Mori, Kazutoshi, Takahashi, Ryosuke, Iinuma, Munekazu, Hori, Osamu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480445/ https://www.ncbi.nlm.nih.gov/pubmed/23112876 http://dx.doi.org/10.1371/journal.pone.0047950 |
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