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An Operant Conditioning Method for Studying Auditory Behaviors in Marmoset Monkeys
The common marmoset (Callithrix jacchus) is a small New World primate that has increasingly been used as a non-human model in the fields of sensory, motor, and cognitive neuroscience. However, little knowledge exists regarding behavioral methods in this species. Developing an understanding of the ne...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480461/ https://www.ncbi.nlm.nih.gov/pubmed/23110123 http://dx.doi.org/10.1371/journal.pone.0047895 |
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author | Remington, Evan D. Osmanski, Michael S. Wang, Xiaoqin |
author_facet | Remington, Evan D. Osmanski, Michael S. Wang, Xiaoqin |
author_sort | Remington, Evan D. |
collection | PubMed |
description | The common marmoset (Callithrix jacchus) is a small New World primate that has increasingly been used as a non-human model in the fields of sensory, motor, and cognitive neuroscience. However, little knowledge exists regarding behavioral methods in this species. Developing an understanding of the neural basis of perception and cognition in an animal model requires measurement of both brain activity and behavior. Here we describe an operant conditioning behavioral training method developed to allow controlled psychoacoustic measurements in marmosets. We demonstrate that marmosets can be trained to consistently perform a Go/No-Go auditory task in which a subject licks at a feeding tube when it detects a sound. Correct responses result in delivery of a food reward. Crucially, this operant conditioning task generates little body movement and is well suited for pairing behavior with single-unit electrophysiology. Successful implementation of an operant conditioning behavior opens the door to a wide range of new studies in the field of auditory neuroscience using the marmoset as a model system. |
format | Online Article Text |
id | pubmed-3480461 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-34804612012-10-29 An Operant Conditioning Method for Studying Auditory Behaviors in Marmoset Monkeys Remington, Evan D. Osmanski, Michael S. Wang, Xiaoqin PLoS One Research Article The common marmoset (Callithrix jacchus) is a small New World primate that has increasingly been used as a non-human model in the fields of sensory, motor, and cognitive neuroscience. However, little knowledge exists regarding behavioral methods in this species. Developing an understanding of the neural basis of perception and cognition in an animal model requires measurement of both brain activity and behavior. Here we describe an operant conditioning behavioral training method developed to allow controlled psychoacoustic measurements in marmosets. We demonstrate that marmosets can be trained to consistently perform a Go/No-Go auditory task in which a subject licks at a feeding tube when it detects a sound. Correct responses result in delivery of a food reward. Crucially, this operant conditioning task generates little body movement and is well suited for pairing behavior with single-unit electrophysiology. Successful implementation of an operant conditioning behavior opens the door to a wide range of new studies in the field of auditory neuroscience using the marmoset as a model system. Public Library of Science 2012-10-24 /pmc/articles/PMC3480461/ /pubmed/23110123 http://dx.doi.org/10.1371/journal.pone.0047895 Text en © 2012 Remington et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Remington, Evan D. Osmanski, Michael S. Wang, Xiaoqin An Operant Conditioning Method for Studying Auditory Behaviors in Marmoset Monkeys |
title | An Operant Conditioning Method for Studying Auditory Behaviors in Marmoset Monkeys |
title_full | An Operant Conditioning Method for Studying Auditory Behaviors in Marmoset Monkeys |
title_fullStr | An Operant Conditioning Method for Studying Auditory Behaviors in Marmoset Monkeys |
title_full_unstemmed | An Operant Conditioning Method for Studying Auditory Behaviors in Marmoset Monkeys |
title_short | An Operant Conditioning Method for Studying Auditory Behaviors in Marmoset Monkeys |
title_sort | operant conditioning method for studying auditory behaviors in marmoset monkeys |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480461/ https://www.ncbi.nlm.nih.gov/pubmed/23110123 http://dx.doi.org/10.1371/journal.pone.0047895 |
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