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IL-4 Haplotype -590T, -34T and Intron-3 VNTR R2 Is Associated with Reduced Malaria Risk among Ancestral Indian Tribal Populations

BACKGROUND: Interleukin 4 (IL-4) is an anti-inflammatory cytokine, which regulates balance between T(H)1 and T(H)2 immune response, immunoglobulin class switching and humoral immunity. Polymorphisms in this gene have been reported to affect the risk of infectious and autoimmune diseases. METHODS: We...

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Detalles Bibliográficos
Autores principales:	Jha, Aditya Nath, Singh, Vipin Kumar, Kumari, Namrata, Singh, Ashish, Antony, Justin, van Tong, Hoang, Singh, Sakshi, Pati, Sudhanshu S., Patra, Pradeep K., Singh, Rajender, Toan, Nguyen L., Song, Le H., Assaf, Amal, Messias–Reason, Iara J. T., Velavan, Thirumalaisamy P., Singh, Lalji, Thangaraj, Kumarasamy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480467/ https://www.ncbi.nlm.nih.gov/pubmed/23110190 http://dx.doi.org/10.1371/journal.pone.0048136

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