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Inflammation and Gli2 Suppress Gastrin Gene Expression in a Murine Model of Antral Hyperplasia
Chronic inflammation in the stomach can lead to gastric cancer. We previously reported that gastrin-deficient (Gast(−/−)) mice develop bacterial overgrowth, inflammatory infiltrate, increased Il-1β expression, antral hyperplasia and eventually antral tumors. Since Hedgehog (Hh) signaling is active i...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480483/ https://www.ncbi.nlm.nih.gov/pubmed/23110168 http://dx.doi.org/10.1371/journal.pone.0048039 |