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Increased Mutability of Staphylococci in Biofilms as a Consequence of Oxidative Stress

OBJECTIVES: To investigate the development of mutational resistance to antibiotics in staphylococcal biofilms. METHODS: Mutation frequencies to resistance against mupirocin and rifampicin were determined for planktonic cultures and for biofilms generated using either a novel static biofilm model or...

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Detalles Bibliográficos
Autores principales: Ryder, Victoria J., Chopra, Ian, O’Neill, Alex J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480535/
https://www.ncbi.nlm.nih.gov/pubmed/23110091
http://dx.doi.org/10.1371/journal.pone.0047695