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Prospective study on retinal nerve fibre layer changes after an acute episode of phacomorphic angle closure

To investigate the retinal nerve fibre layer (RNFL) changes after an acute attack of phacomorphic angle closure. This prospective study involved ten cases of phacomorphic angle closure that underwent cataract extraction and intraocular lens insertion after intraocular pressure lowering. Apart from v...

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Autores principales: Lee, Jacky W. Y., Lai, Jimmy S. M., Yick, Doris W. F., Yuen, Can Y. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480582/
https://www.ncbi.nlm.nih.gov/pubmed/22847248
http://dx.doi.org/10.1007/s10792-012-9614-5
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author Lee, Jacky W. Y.
Lai, Jimmy S. M.
Yick, Doris W. F.
Yuen, Can Y. F.
author_facet Lee, Jacky W. Y.
Lai, Jimmy S. M.
Yick, Doris W. F.
Yuen, Can Y. F.
author_sort Lee, Jacky W. Y.
collection PubMed
description To investigate the retinal nerve fibre layer (RNFL) changes after an acute attack of phacomorphic angle closure. This prospective study involved ten cases of phacomorphic angle closure that underwent cataract extraction and intraocular lens insertion after intraocular pressure lowering. Apart from visual acuity and intraocular pressure (IOP), RNFL thickness and vertical cup disc ratio (VCDR) were measured by optical coherence tomography (OCT) at 3–9 months post attack. Humphrey visual field assessment was performed at 9 months post attack. All cases had mean phacomorphic duration of <5 days. Postoperatively, best correct Snellen visual acuity was 0.4 ± 0.2 and IOP at 9 months was 11.0 ± 3.1 mmHg. There was no difference in VCDR and RNFL between the attack and contralateral eye at 3 months post attack (both p = 0.4). At 9 months post attack, there was significant thinning in the average (p = 0.01), superior (p = 0.01), and inferior (p = 0.006) RNFL. There was no significant difference in the pattern standard deviation (PSD) between the two eyes on the Humphrey visual field nor was there any correlation between PSD severity and RNFL thinning (all p > 0.2. Patients with <5 days duration of phacomorphic angle closure are likely to have reasonable postoperative vision. An acute episode of phacomorphic angle closure can trigger an accelerated RNFL thinning despite normal IOP and open angles, most noticeable in the superior and inferior quadrants, occurring between 3 and 9 months post attack. Glaucomatous optic neuropathy in the attack eye was evident by OCT but not by visual field assessment at the same time interval.
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spelling pubmed-34805822012-11-01 Prospective study on retinal nerve fibre layer changes after an acute episode of phacomorphic angle closure Lee, Jacky W. Y. Lai, Jimmy S. M. Yick, Doris W. F. Yuen, Can Y. F. Int Ophthalmol Original Paper To investigate the retinal nerve fibre layer (RNFL) changes after an acute attack of phacomorphic angle closure. This prospective study involved ten cases of phacomorphic angle closure that underwent cataract extraction and intraocular lens insertion after intraocular pressure lowering. Apart from visual acuity and intraocular pressure (IOP), RNFL thickness and vertical cup disc ratio (VCDR) were measured by optical coherence tomography (OCT) at 3–9 months post attack. Humphrey visual field assessment was performed at 9 months post attack. All cases had mean phacomorphic duration of <5 days. Postoperatively, best correct Snellen visual acuity was 0.4 ± 0.2 and IOP at 9 months was 11.0 ± 3.1 mmHg. There was no difference in VCDR and RNFL between the attack and contralateral eye at 3 months post attack (both p = 0.4). At 9 months post attack, there was significant thinning in the average (p = 0.01), superior (p = 0.01), and inferior (p = 0.006) RNFL. There was no significant difference in the pattern standard deviation (PSD) between the two eyes on the Humphrey visual field nor was there any correlation between PSD severity and RNFL thinning (all p > 0.2. Patients with <5 days duration of phacomorphic angle closure are likely to have reasonable postoperative vision. An acute episode of phacomorphic angle closure can trigger an accelerated RNFL thinning despite normal IOP and open angles, most noticeable in the superior and inferior quadrants, occurring between 3 and 9 months post attack. Glaucomatous optic neuropathy in the attack eye was evident by OCT but not by visual field assessment at the same time interval. Springer Netherlands 2012-07-31 2012 /pmc/articles/PMC3480582/ /pubmed/22847248 http://dx.doi.org/10.1007/s10792-012-9614-5 Text en © The Author(s) 2012 https://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Original Paper
Lee, Jacky W. Y.
Lai, Jimmy S. M.
Yick, Doris W. F.
Yuen, Can Y. F.
Prospective study on retinal nerve fibre layer changes after an acute episode of phacomorphic angle closure
title Prospective study on retinal nerve fibre layer changes after an acute episode of phacomorphic angle closure
title_full Prospective study on retinal nerve fibre layer changes after an acute episode of phacomorphic angle closure
title_fullStr Prospective study on retinal nerve fibre layer changes after an acute episode of phacomorphic angle closure
title_full_unstemmed Prospective study on retinal nerve fibre layer changes after an acute episode of phacomorphic angle closure
title_short Prospective study on retinal nerve fibre layer changes after an acute episode of phacomorphic angle closure
title_sort prospective study on retinal nerve fibre layer changes after an acute episode of phacomorphic angle closure
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480582/
https://www.ncbi.nlm.nih.gov/pubmed/22847248
http://dx.doi.org/10.1007/s10792-012-9614-5
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