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Antineoplastic activity of the DNA methyltransferase inhibitor 5-aza-2′-deoxycytidine in anaplastic large cell lymphoma

DNA methylation is an epigenetic mechanism establishing long-term gene silencing during development and cell commitment, which is maintained in subsequent cell generations. Aberrant DNA methylation is found at gene promoters in most cancers and can lead to silencing of tumor suppressor genes. The DN...

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Detalles Bibliográficos
Autores principales:	Hassler, Melanie R., Klisaroska, Aleksandra, Kollmann, Karoline, Steiner, Irene, Bilban, Martin, Schiefer, Ana-Iris, Sexl, Veronika, Egger, Gerda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editions Scientifiques Elsevier 2012
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480637/ https://www.ncbi.nlm.nih.gov/pubmed/22687603 http://dx.doi.org/10.1016/j.biochi.2012.05.029

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