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Repo-Man Coordinates Chromosomal Reorganization with Nuclear Envelope Reassembly during Mitotic Exit

Repo-Man targets protein phosphatase 1 γ (PP1γ) to chromatin at anaphase onset and regulates chromosome structure during mitotic exit. Here, we show that a Repo-Man:PP1 complex forms in anaphase following dephosphorylation of Repo-Man. Upon activation, the complex localizes to chromosomes and causes...

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Detalles Bibliográficos
Autores principales: Vagnarelli, Paola, Ribeiro, Susana, Sennels, Lau, Sanchez-Pulido, Luis, de Lima Alves, Flavia, Verheyen, Toon, Kelly, David A., Ponting, Chris P., Rappsilber, Juri, Earnshaw, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480639/
https://www.ncbi.nlm.nih.gov/pubmed/21820363
http://dx.doi.org/10.1016/j.devcel.2011.06.020