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Repo-Man Coordinates Chromosomal Reorganization with Nuclear Envelope Reassembly during Mitotic Exit
Repo-Man targets protein phosphatase 1 γ (PP1γ) to chromatin at anaphase onset and regulates chromosome structure during mitotic exit. Here, we show that a Repo-Man:PP1 complex forms in anaphase following dephosphorylation of Repo-Man. Upon activation, the complex localizes to chromosomes and causes...
Autores principales: | Vagnarelli, Paola, Ribeiro, Susana, Sennels, Lau, Sanchez-Pulido, Luis, de Lima Alves, Flavia, Verheyen, Toon, Kelly, David A., Ponting, Chris P., Rappsilber, Juri, Earnshaw, William C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480639/ https://www.ncbi.nlm.nih.gov/pubmed/21820363 http://dx.doi.org/10.1016/j.devcel.2011.06.020 |
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