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Phosphatidylethanolamine and Cardiolipin Differentially Affect the Stability of Mitochondrial Respiratory Chain Supercomplexes
The mitochondrial inner membrane contains two non-bilayer‐forming phospholipids, phosphatidylethanolamine (PE) and cardiolipin (CL). Lack of CL leads to destabilization of respiratory chain supercomplexes, a reduced activity of cytochrome c oxidase, and a reduced inner membrane potential Δψ. Althoug...
Autores principales: | Böttinger, Lena, Horvath, Susanne E., Kleinschroth, Thomas, Hunte, Carola, Daum, Günther, Pfanner, Nikolaus, Becker, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480645/ https://www.ncbi.nlm.nih.gov/pubmed/22971339 http://dx.doi.org/10.1016/j.jmb.2012.09.001 |
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