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Virtual Screening for Finding Novel COX-2 Inhibitors as Antitumor Agents
The cyclooxygenase-2 (COX-2) enzyme binds to arachidonic acid resulting in the release of metabolites that induce pain and inflammatory responses. Recent studies have shown that strong COX-2 expression is highly correlated with increased tumor risk. Therefore, the development of potent COX-2 inhibit...
Autores principales: | Badieyan, Zohreh S, Moallem, Seyed Adel, Mehri, Soghra, Shahsavand, Shabnam, Hadizadeh, Farzin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Open
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480690/ https://www.ncbi.nlm.nih.gov/pubmed/23115597 http://dx.doi.org/10.2174/1874104501206010015 |
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