Cargando…
Choline Analogues in Malaria Chemotherapy
Emerging resistance against well-established anti-malaria drugs warrants the introduction of new therapeutic agents with original mechanisms of action. Inhibition of membrane-based phospholipid biosynthesis, which is crucial for the parasite, has thus been proposed as a novel and promising therapeut...
Autores principales: | Peyrottes, Suzanne, Caldarelli, Sergio, Wein, Sharon, Périgaud, Christian, Pellet, Alain, Vial, Henri |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480700/ https://www.ncbi.nlm.nih.gov/pubmed/22607139 http://dx.doi.org/10.2174/138161212801327338 |
Ejemplares similares
-
Synthesis of (R)- and (S)-β-hydroxyphosphonate acyclonucleosides: structural analogues of Adefovir (PMEA)
por: Kasthuri, Mahesh, et al.
Publicado: (2011) -
Synthesis and substrate properties towards HIV-1 reverse transcriptase of new diphosphate analogues of 9-[(2-phosphonomethoxy)ethyl]adenine
por: Laux, Wolfgang HG, et al.
Publicado: (2018) -
Contribution of the precursors and interplay of the pathways in the phospholipid metabolism of the malaria parasite
por: Wein, Sharon, et al.
Publicado: (2018) -
Structural Insights into the Inhibition of Cytosolic 5′-Nucleotidase II (cN-II) by Ribonucleoside 5′-Monophosphate Analogues
por: Gallier, Franck, et al.
Publicado: (2011) -
Beta-hydroxyphosphonate ribonucleoside analogues derived from 4-substituted-1,2,3-triazoles as IMP/GMP mimics: synthesis and biological evaluation
por: Nguyen Van, Tai, et al.
Publicado: (2016)