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Evidence of widespread selection on standing variation in Europe at height-associated SNPs

Strong signatures of positive selection at newly arising genetic variants are well-documented in humans(1–8), but this form of selection may not be widespread in recent human evolution(9). Because many human traits are highly polygenic and partly determined by common, ancient genetic variation, an a...

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Detalles Bibliográficos
Autores principales: Turchin, Michael C., Chiang, Charleston W. K., Palmer, Cameron D., Sankararaman, Sriram, Reich, David, Hirschhorn, Joel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480734/
https://www.ncbi.nlm.nih.gov/pubmed/22902787
http://dx.doi.org/10.1038/ng.2368