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Divergence of sperm and leukocyte age-dependent telomere dynamics: implications for male-driven evolution of telomere length in humans
Telomere length (TL) dynamics in vivo are defined by TL and its age-dependent change, brought about by cell replication. Leukocyte TL (LTL), which reflects TL in hematopoietic stem cells (HSCs), becomes shorter with age. In contrast, sperm TL, which reflects TL in the male germ cells, becomes longer...
Autores principales: | Aston, Kenneth I., Hunt, Steven C., Susser, Ezra, Kimura, Masayuki, Factor-Litvak, Pam, Carrell, Douglas, Aviv, Abraham |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480822/ https://www.ncbi.nlm.nih.gov/pubmed/22782639 http://dx.doi.org/10.1093/molehr/gas028 |
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