Low or undetectable TPO receptor expression in malignant tissue and cell lines derived from breast, lung, and ovarian tumors

BACKGROUND: Numerous efficacious chemotherapy regimens may cause thrombocytopenia. Thrombopoietin receptor (TPO-R) agonists, such as eltrombopag, represent a novel approach for the treatment of chemotherapy-induced thrombocytopenia. The TPO-R MPL is expressed on megakaryocytes and megakaryocyte prec...

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Detalles Bibliográficos
Autores principales: Erickson-Miller, Connie L, Pillarisetti, Kodandaram, Kirchner, Jennifer, Figueroa, David J, Ottesen, Lone, Martin, Anne-Marie, Liu, Yuan, Kamel, Yasser Mostafa, Messam, Conrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480928/
https://www.ncbi.nlm.nih.gov/pubmed/22967017
http://dx.doi.org/10.1186/1471-2407-12-405

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