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Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure

Inflammation enhances the secretion of sphingomyelinases (SMases). SMases catalyze the hydrolysis of sphingomyelin into phosphocholine and ceramide. In erythrocytes, ceramide formation leads to exposure of the removal signal phosphatidylserine (PS), creating a potential link between SMase activity a...

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Detalles Bibliográficos
Autores principales: Dinkla, S, Wessels, K, Verdurmen, W P R, Tomelleri, C, Cluitmans, J C A, Fransen, J, Fuchs, B, Schiller, J, Joosten, I, Brock, R, Bosman, G J C G M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481131/
https://www.ncbi.nlm.nih.gov/pubmed/23076218
http://dx.doi.org/10.1038/cddis.2012.143

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