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Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure
Inflammation enhances the secretion of sphingomyelinases (SMases). SMases catalyze the hydrolysis of sphingomyelin into phosphocholine and ceramide. In erythrocytes, ceramide formation leads to exposure of the removal signal phosphatidylserine (PS), creating a potential link between SMase activity a...
Autores principales: | Dinkla, S, Wessels, K, Verdurmen, W P R, Tomelleri, C, Cluitmans, J C A, Fransen, J, Fuchs, B, Schiller, J, Joosten, I, Brock, R, Bosman, G J C G M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481131/ https://www.ncbi.nlm.nih.gov/pubmed/23076218 http://dx.doi.org/10.1038/cddis.2012.143 |
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