The microRNA-26a target E2F7 sustains cell proliferation and inhibits monocytic differentiation of acute myeloid leukemia cells

Blocks in genetic programs required for terminal myeloid differentiation and aberrant proliferation characterize acute myeloid leukemia (AML) cells. 1,25-Dihydroxy-vitamin D3 (VitD3) arrests proliferation of AML cells and induces their differentiation into mature monocytes. In a previous study, we s...

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Detalles Bibliográficos
Autores principales: Salvatori, B, Iosue, I, Mangiavacchi, A, Loddo, G, Padula, F, Chiaretti, S, Peragine, N, Bozzoni, I, Fazi, F, Fatica, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481138/
https://www.ncbi.nlm.nih.gov/pubmed/23096114
http://dx.doi.org/10.1038/cddis.2012.151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481138/
https://www.ncbi.nlm.nih.gov/pubmed/23096114
http://dx.doi.org/10.1038/cddis.2012.151

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