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The microRNA-26a target E2F7 sustains cell proliferation and inhibits monocytic differentiation of acute myeloid leukemia cells
Blocks in genetic programs required for terminal myeloid differentiation and aberrant proliferation characterize acute myeloid leukemia (AML) cells. 1,25-Dihydroxy-vitamin D3 (VitD3) arrests proliferation of AML cells and induces their differentiation into mature monocytes. In a previous study, we s...
Autores principales: | Salvatori, B, Iosue, I, Mangiavacchi, A, Loddo, G, Padula, F, Chiaretti, S, Peragine, N, Bozzoni, I, Fazi, F, Fatica, A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481138/ https://www.ncbi.nlm.nih.gov/pubmed/23096114 http://dx.doi.org/10.1038/cddis.2012.151 |
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