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Amyloid β-Sheet Mimics that Antagonize Amyloid Aggregation and Reduce Amyloid Toxicity
The amyloid protein aggregation associated with diseases such as Alzheimer’s, Parkinson’s, and type II diabetes (among many others), features a bewildering variety of β-sheet-rich structures in transition from native proteins to ordered oligomers and fibers. The variation in the amino acid sequences...
Autores principales: | Cheng, Pin-Nan, Liu, Cong, Zhao, Minglei, Eisenberg, David, Nowick, James S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481199/ https://www.ncbi.nlm.nih.gov/pubmed/23089868 http://dx.doi.org/10.1038/nchem.1433 |
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