Cargando…
CRASH-3 - tranexamic acid for the treatment of significant traumatic brain injury: study protocol for an international randomized, double-blind, placebo-controlled trial
BACKGROUND: Worldwide, over 10 million people are killed or hospitalized because of traumatic brain injury each year. About 90% of deaths occur in low- and middle-income countries. The condition mostly affects young adults, and many experience long lasting or permanent disability. The social and eco...
Autores principales: | Dewan, Yashbir, Komolafe, Edward O, Mejía-Mantilla, Jorge H, Perel, Pablo, Roberts, Ian, Shakur, Haleema |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481366/ https://www.ncbi.nlm.nih.gov/pubmed/22721545 http://dx.doi.org/10.1186/1745-6215-13-87 |
Ejemplares similares
-
Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial
por: Roberts, Ian, et al.
Publicado: (2018) -
A nested mechanistic sub-study into the effect of tranexamic acid versus placebo on intracranial haemorrhage and cerebral ischaemia in isolated traumatic brain injury: study protocol for a randomised controlled trial (CRASH-3 Trial Intracranial Bleeding Mechanistic Sub-Study [CRASH-3 IBMS])
por: Mahmood, Abda, et al.
Publicado: (2017) -
Cost-Effectiveness Analysis of Administering Tranexamic Acid to
Bleeding Trauma Patients Using Evidence from the CRASH-2 Trial
por: Guerriero, Carla, et al.
Publicado: (2011) -
The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an international randomised, double blind placebo controlled trial
por: Shakur, Haleema, et al.
Publicado: (2010) -
Avoidable mortality from giving tranexamic acid to bleeding trauma patients: an estimation based on WHO mortality data, a systematic literature review and data from the CRASH-2 trial
por: Ker, Katharine, et al.
Publicado: (2012)