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ISway: a sensitive, valid and reliable measure of postural control

BACKGROUND: Clinicians need a practical, objective test of postural control that is sensitive to mild neurological disease, shows experimental and clinical validity, and has good test-retest reliability. We developed an instrumented test of postural sway (ISway) using a body-worn accelerometer to of...

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Autores principales: Mancini, Martina, Salarian, Arash, Carlson-Kuhta, Patricia, Zampieri, Cris, King, Laurie, Chiari, Lorenzo, Horak, Fay B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481400/
https://www.ncbi.nlm.nih.gov/pubmed/22913719
http://dx.doi.org/10.1186/1743-0003-9-59
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author Mancini, Martina
Salarian, Arash
Carlson-Kuhta, Patricia
Zampieri, Cris
King, Laurie
Chiari, Lorenzo
Horak, Fay B
author_facet Mancini, Martina
Salarian, Arash
Carlson-Kuhta, Patricia
Zampieri, Cris
King, Laurie
Chiari, Lorenzo
Horak, Fay B
author_sort Mancini, Martina
collection PubMed
description BACKGROUND: Clinicians need a practical, objective test of postural control that is sensitive to mild neurological disease, shows experimental and clinical validity, and has good test-retest reliability. We developed an instrumented test of postural sway (ISway) using a body-worn accelerometer to offer an objective and practical measure of postural control. METHODS: We conducted two separate studies with two groups of subjects. Study I: sensitivity and experimental concurrent validity. Thirteen subjects with early, untreated Parkinson’s disease (PD) and 12 age-matched control subjects (CTR) were tested in the laboratory, to compare sway from force-plate COP and inertial sensors. Study II: test-retest reliability and clinical concurrent validity. A different set of 17 early-to-moderate, treated PD (tested ON medication), and 17 age-matched CTR subjects were tested in the clinic to compare clinical balance tests with sway from inertial sensors. For reliability, the sensor was removed, subjects rested for 30 min, and the protocol was repeated. Thirteen sway measures (7 time-domain, 5 frequency-domain measures, and JERK) were computed from the 2D time series acceleration (ACC) data to determine the best metrics for a clinical balance test. RESULTS: Both center of pressure (COP) and ACC measures differentiated sway between CTR and untreated PD. JERK and time-domain measures showed the best test-retest reliability (JERK ICC was 0.86 in PD and 0.87 in CTR; time-domain measures ICC ranged from 0.55 to 0.84 in PD and from 0.60 to 0.89 in CTR). JERK, all but one time-domain measure, and one frequency measure were significantly correlated with the clinical postural stability score (r ranged from 0.50 to 0.63, 0.01 < p < 0.05). CONCLUSIONS: Based on these results, we recommend a subset of the most sensitive, reliable, and valid ISway measures to characterize posture control in PD: 1) JERK, 2) RMS amplitude and mean velocity from the time-domain measures, and 3) centroidal frequency as the best frequency measure, as valid and reliable measures of balance control from ISway.
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spelling pubmed-34814002012-11-02 ISway: a sensitive, valid and reliable measure of postural control Mancini, Martina Salarian, Arash Carlson-Kuhta, Patricia Zampieri, Cris King, Laurie Chiari, Lorenzo Horak, Fay B J Neuroeng Rehabil Research BACKGROUND: Clinicians need a practical, objective test of postural control that is sensitive to mild neurological disease, shows experimental and clinical validity, and has good test-retest reliability. We developed an instrumented test of postural sway (ISway) using a body-worn accelerometer to offer an objective and practical measure of postural control. METHODS: We conducted two separate studies with two groups of subjects. Study I: sensitivity and experimental concurrent validity. Thirteen subjects with early, untreated Parkinson’s disease (PD) and 12 age-matched control subjects (CTR) were tested in the laboratory, to compare sway from force-plate COP and inertial sensors. Study II: test-retest reliability and clinical concurrent validity. A different set of 17 early-to-moderate, treated PD (tested ON medication), and 17 age-matched CTR subjects were tested in the clinic to compare clinical balance tests with sway from inertial sensors. For reliability, the sensor was removed, subjects rested for 30 min, and the protocol was repeated. Thirteen sway measures (7 time-domain, 5 frequency-domain measures, and JERK) were computed from the 2D time series acceleration (ACC) data to determine the best metrics for a clinical balance test. RESULTS: Both center of pressure (COP) and ACC measures differentiated sway between CTR and untreated PD. JERK and time-domain measures showed the best test-retest reliability (JERK ICC was 0.86 in PD and 0.87 in CTR; time-domain measures ICC ranged from 0.55 to 0.84 in PD and from 0.60 to 0.89 in CTR). JERK, all but one time-domain measure, and one frequency measure were significantly correlated with the clinical postural stability score (r ranged from 0.50 to 0.63, 0.01 < p < 0.05). CONCLUSIONS: Based on these results, we recommend a subset of the most sensitive, reliable, and valid ISway measures to characterize posture control in PD: 1) JERK, 2) RMS amplitude and mean velocity from the time-domain measures, and 3) centroidal frequency as the best frequency measure, as valid and reliable measures of balance control from ISway. BioMed Central 2012-08-22 /pmc/articles/PMC3481400/ /pubmed/22913719 http://dx.doi.org/10.1186/1743-0003-9-59 Text en Copyright ©2012 Mancini et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Mancini, Martina
Salarian, Arash
Carlson-Kuhta, Patricia
Zampieri, Cris
King, Laurie
Chiari, Lorenzo
Horak, Fay B
ISway: a sensitive, valid and reliable measure of postural control
title ISway: a sensitive, valid and reliable measure of postural control
title_full ISway: a sensitive, valid and reliable measure of postural control
title_fullStr ISway: a sensitive, valid and reliable measure of postural control
title_full_unstemmed ISway: a sensitive, valid and reliable measure of postural control
title_short ISway: a sensitive, valid and reliable measure of postural control
title_sort isway: a sensitive, valid and reliable measure of postural control
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481400/
https://www.ncbi.nlm.nih.gov/pubmed/22913719
http://dx.doi.org/10.1186/1743-0003-9-59
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