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Epidemiological Features of Visceral Leishmaniasis in Fars Province, Southern Iran
BACKGROUND: To describe the epidemiological features of pediatric visceral leishmaniasis in southern Iran. METHODS: This retrospective study was carried out using local hospital records of VL patients from 2001 through 2009. Data such as age, gender, place of residence, clinical signs and symptoms,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tehran University of Medical Sciences
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481615/ https://www.ncbi.nlm.nih.gov/pubmed/23113170 |
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author | Sarkari, B Hatam, G Ghatee, MA |
author_facet | Sarkari, B Hatam, G Ghatee, MA |
author_sort | Sarkari, B |
collection | PubMed |
description | BACKGROUND: To describe the epidemiological features of pediatric visceral leishmaniasis in southern Iran. METHODS: This retrospective study was carried out using local hospital records of VL patients from 2001 through 2009. Data such as age, gender, place of residence, clinical signs and symptoms, treatment, history of recurrence were recorded. The collected data were statistically analyzed using SPSS software. RESULTS: A total of 260 cases of VL have been recorded during 2001 to 2009 in south of Iran, based on hospital records. Mean age of patients was 3.5 years with the highest prevalence in 2 years old patients. The diseases have been more common in males (60%). The main clinical signs and symptoms of the patients were fever (96.2%), hepatosplenomegaly (68.8%) and abdominal protrusion (71.9%). Most of cases were from Kazeroun County (17.5%) in Fars Province followed by Borazjan in Boushehr Province. Bone marrow aspirations have been performed in 178 of cases and Leishmania amastigotes were detected in only 50 (28.1%) cases. Glucantime has been the first drug treatment while 19.3% of cases have been treated with amphotericin B. Mortality rate was 6.2% and children under 1 year old have been the main victim of the disease. Relapse has been noted in 7.3% of patients. CONCLUSION: VL is still endemic in South of Iran, especially in Fars Province with a noticeable mortality rate. Moreover, cases of the diseases are reporting from neighboring provinces and this might be due to the spreading of the diseases to the adjacent provinces. |
format | Online Article Text |
id | pubmed-3481615 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Tehran University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-34816152012-10-30 Epidemiological Features of Visceral Leishmaniasis in Fars Province, Southern Iran Sarkari, B Hatam, G Ghatee, MA Iran J Public Health Original Article BACKGROUND: To describe the epidemiological features of pediatric visceral leishmaniasis in southern Iran. METHODS: This retrospective study was carried out using local hospital records of VL patients from 2001 through 2009. Data such as age, gender, place of residence, clinical signs and symptoms, treatment, history of recurrence were recorded. The collected data were statistically analyzed using SPSS software. RESULTS: A total of 260 cases of VL have been recorded during 2001 to 2009 in south of Iran, based on hospital records. Mean age of patients was 3.5 years with the highest prevalence in 2 years old patients. The diseases have been more common in males (60%). The main clinical signs and symptoms of the patients were fever (96.2%), hepatosplenomegaly (68.8%) and abdominal protrusion (71.9%). Most of cases were from Kazeroun County (17.5%) in Fars Province followed by Borazjan in Boushehr Province. Bone marrow aspirations have been performed in 178 of cases and Leishmania amastigotes were detected in only 50 (28.1%) cases. Glucantime has been the first drug treatment while 19.3% of cases have been treated with amphotericin B. Mortality rate was 6.2% and children under 1 year old have been the main victim of the disease. Relapse has been noted in 7.3% of patients. CONCLUSION: VL is still endemic in South of Iran, especially in Fars Province with a noticeable mortality rate. Moreover, cases of the diseases are reporting from neighboring provinces and this might be due to the spreading of the diseases to the adjacent provinces. Tehran University of Medical Sciences 2012-04-30 /pmc/articles/PMC3481615/ /pubmed/23113170 Text en Copyright © Iranian Public Health Association & Tehran University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly. |
spellingShingle | Original Article Sarkari, B Hatam, G Ghatee, MA Epidemiological Features of Visceral Leishmaniasis in Fars Province, Southern Iran |
title | Epidemiological Features of Visceral Leishmaniasis in Fars Province, Southern Iran |
title_full | Epidemiological Features of Visceral Leishmaniasis in Fars Province, Southern Iran |
title_fullStr | Epidemiological Features of Visceral Leishmaniasis in Fars Province, Southern Iran |
title_full_unstemmed | Epidemiological Features of Visceral Leishmaniasis in Fars Province, Southern Iran |
title_short | Epidemiological Features of Visceral Leishmaniasis in Fars Province, Southern Iran |
title_sort | epidemiological features of visceral leishmaniasis in fars province, southern iran |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481615/ https://www.ncbi.nlm.nih.gov/pubmed/23113170 |
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