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An unusual case of dapsone syndrome
Dapsone, a potent antiparasitic and anti-inflammatory compound, is mainly used in the treatment of leprosy and a variety of blistering skin diseases. It may cause a severe adverse drug reaction with multiorgan involvement known as dapsone hypersensitivity syndrome. We report an unusual case of dapso...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications Pvt Ltd
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481807/ https://www.ncbi.nlm.nih.gov/pubmed/23130233 http://dx.doi.org/10.4103/2229-5178.85999 |
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author | Grace, Mary |
author_facet | Grace, Mary |
author_sort | Grace, Mary |
collection | PubMed |
description | Dapsone, a potent antiparasitic and anti-inflammatory compound, is mainly used in the treatment of leprosy and a variety of blistering skin diseases. It may cause a severe adverse drug reaction with multiorgan involvement known as dapsone hypersensitivity syndrome. We report an unusual case of dapsone hypersensitivity, manifesting as bone marrow suppression and peripheral pancytopenia in addition to fever, rash, and hepatosplenomegaly. |
format | Online Article Text |
id | pubmed-3481807 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Medknow Publications Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-34818072012-11-05 An unusual case of dapsone syndrome Grace, Mary Indian Dermatol Online J Case Report Dapsone, a potent antiparasitic and anti-inflammatory compound, is mainly used in the treatment of leprosy and a variety of blistering skin diseases. It may cause a severe adverse drug reaction with multiorgan involvement known as dapsone hypersensitivity syndrome. We report an unusual case of dapsone hypersensitivity, manifesting as bone marrow suppression and peripheral pancytopenia in addition to fever, rash, and hepatosplenomegaly. Medknow Publications Pvt Ltd 2011 /pmc/articles/PMC3481807/ /pubmed/23130233 http://dx.doi.org/10.4103/2229-5178.85999 Text en Copyright: © Indian Dermatology Online Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Grace, Mary An unusual case of dapsone syndrome |
title | An unusual case of dapsone syndrome |
title_full | An unusual case of dapsone syndrome |
title_fullStr | An unusual case of dapsone syndrome |
title_full_unstemmed | An unusual case of dapsone syndrome |
title_short | An unusual case of dapsone syndrome |
title_sort | unusual case of dapsone syndrome |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481807/ https://www.ncbi.nlm.nih.gov/pubmed/23130233 http://dx.doi.org/10.4103/2229-5178.85999 |
work_keys_str_mv | AT gracemary anunusualcaseofdapsonesyndrome AT gracemary unusualcaseofdapsonesyndrome |