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‘Venetian blinds’ artifact in dermatohistopathology

The ‘Venetian blinds’ artifact is an uncommon tissue cutting artifact that leads to the formation of parallel series of strips of tissue separated from one another by narrow clear spaces. It has been attributed to either hardening of the tissue in the paraffin block or defective assembly of the micr...

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Autor principal: Joshi, Rajiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481930/
https://www.ncbi.nlm.nih.gov/pubmed/23130268
http://dx.doi.org/10.4103/2229-5178.93497
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author Joshi, Rajiv
author_facet Joshi, Rajiv
author_sort Joshi, Rajiv
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description The ‘Venetian blinds’ artifact is an uncommon tissue cutting artifact that leads to the formation of parallel series of strips of tissue separated from one another by narrow clear spaces. It has been attributed to either hardening of the tissue in the paraffin block or defective assembly of the microtome knife. This artifact occurs in both inflammatory and neoplastic conditions in which there are nodular collections of cells and may reflect vibration-induced disintegration of fragile cellular aggregates that lack dermal stromal support. At scanning magnification, it serves to draw the histopathologist's eye to the site of pathology.
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spelling pubmed-34819302012-11-05 ‘Venetian blinds’ artifact in dermatohistopathology Joshi, Rajiv Indian Dermatol Online J Musings/Opinions/Tips and Experiences The ‘Venetian blinds’ artifact is an uncommon tissue cutting artifact that leads to the formation of parallel series of strips of tissue separated from one another by narrow clear spaces. It has been attributed to either hardening of the tissue in the paraffin block or defective assembly of the microtome knife. This artifact occurs in both inflammatory and neoplastic conditions in which there are nodular collections of cells and may reflect vibration-induced disintegration of fragile cellular aggregates that lack dermal stromal support. At scanning magnification, it serves to draw the histopathologist's eye to the site of pathology. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3481930/ /pubmed/23130268 http://dx.doi.org/10.4103/2229-5178.93497 Text en Copyright: © Indian Dermatology Online Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Musings/Opinions/Tips and Experiences
Joshi, Rajiv
‘Venetian blinds’ artifact in dermatohistopathology
title ‘Venetian blinds’ artifact in dermatohistopathology
title_full ‘Venetian blinds’ artifact in dermatohistopathology
title_fullStr ‘Venetian blinds’ artifact in dermatohistopathology
title_full_unstemmed ‘Venetian blinds’ artifact in dermatohistopathology
title_short ‘Venetian blinds’ artifact in dermatohistopathology
title_sort ‘venetian blinds’ artifact in dermatohistopathology
topic Musings/Opinions/Tips and Experiences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481930/
https://www.ncbi.nlm.nih.gov/pubmed/23130268
http://dx.doi.org/10.4103/2229-5178.93497
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