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Loss of sfrp1 promotes ductal branching in the murine mammary gland

BACKGROUND: Secreted frizzled-related proteins (SFRPs) are a family of proteins that block the Wnt signaling pathway and loss of SFRP1 expression is found in breast cancer along with a multitude of other human cancers. Activated Wnt signaling leads to inappropriate mammary gland development and mamm...

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Detalles Bibliográficos
Autores principales:	Gauger, Kelly J, Shimono, Akihiko, Crisi, Giovanna M, Schneider, Sallie Smith
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482146/ https://www.ncbi.nlm.nih.gov/pubmed/22928951 http://dx.doi.org/10.1186/1471-213X-12-25

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