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Dimethylarginine Dimethylaminohydrolase1 Is an Organ-Specific Mediator of End Organ Damage in a Murine Model of Hypertension

BACKGROUND: The endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine (ADMA) is an independent predictor of cardiovascular and overall mortality. Moreover, elevated ADMA plasma concentrations are associated with the extent of hypertension. However, data from small-sized clinical tri...

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Detalles Bibliográficos
Autores principales:	Sydow, Karsten, Schmitz, Christine, von Leitner, Eike-Christin, von Leitner, Robin, Klinke, Anna, Atzler, Dorothee, Krebs, Christian, Wieboldt, Hartwig, Ehmke, Heimo, Schwedhelm, Edzard, Meinertz, Thomas, Blankenberg, Stefan, Böger, Rainer H., Magnus, Tim, Baldus, Stephan, Wenzel, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482201/ https://www.ncbi.nlm.nih.gov/pubmed/23110194 http://dx.doi.org/10.1371/journal.pone.0048150

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