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Limited T Cell Receptor Repertoire Diversity in Tuberculosis Patients Correlates with Clinical Severity
BACKGROUND: The importance of CD4(+) and CD8(+) T cells in protection against tuberculosis (TB) is well known, however, the association between changes to the T cell repertoire and disease presentation has never been analyzed. Characterization of T-cells in TB patients in previous study only analyze...
Autores principales: | Luo, Wei, Su, Jin, Zhang, Xiao-Bing, Yang, Zhi, Zhou, Ming-Qian, Jiang, Zhen-Min, Hao, Pei-Pei, Liu, Su-Dong, Wen, Qian, Jin, Qi, Ma, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482216/ https://www.ncbi.nlm.nih.gov/pubmed/23110186 http://dx.doi.org/10.1371/journal.pone.0048117 |
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