The Ubiquitin Ligase Nedd4-1 Participates in Denervation-Induced Skeletal Muscle Atrophy in Mice

Skeletal muscle atrophy is a consequence of muscle inactivity resulting from denervation, unloading and immobility. It accompanies many chronic disease states and also occurs as a pathophysiologic consequence of normal aging. In all these conditions, ubiquitin-dependent proteolysis is a key regulato...

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Detalles Bibliográficos
Autores principales: Nagpal, Preena, Plant, Pamela J., Correa, Judy, Bain, Alexandra, Takeda, Michiko, Kawabe, Hiroshi, Rotin, Daniela, Bain, James R., Batt, Jane A. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482220/
https://www.ncbi.nlm.nih.gov/pubmed/23110050
http://dx.doi.org/10.1371/journal.pone.0046427

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