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Bilateral Theta-Burst TMS to Influence Global Gestalt Perception

While early and higher visual areas along the ventral visual pathway in the inferotemporal cortex are critical for the recognition of individual objects, the neural representation of human perception of complex global visual scenes remains under debate. Stroke patients with a selective deficit in th...

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Autores principales: Ritzinger, Bernd, Huberle, Elisabeth, Karnath, Hans-Otto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482242/
https://www.ncbi.nlm.nih.gov/pubmed/23110106
http://dx.doi.org/10.1371/journal.pone.0047820
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author Ritzinger, Bernd
Huberle, Elisabeth
Karnath, Hans-Otto
author_facet Ritzinger, Bernd
Huberle, Elisabeth
Karnath, Hans-Otto
author_sort Ritzinger, Bernd
collection PubMed
description While early and higher visual areas along the ventral visual pathway in the inferotemporal cortex are critical for the recognition of individual objects, the neural representation of human perception of complex global visual scenes remains under debate. Stroke patients with a selective deficit in the perception of a complex global Gestalt with intact recognition of individual objects – a deficit termed simultanagnosia – greatly helped to study this question. Interestingly, simultanagnosia typically results from bilateral lesions of the temporo-parietal junction (TPJ). The present study aimed to verify the relevance of this area for human global Gestalt perception. We applied continuous theta-burst TMS either unilaterally (left or right) or bilateral simultaneously over TPJ. Healthy subjects were presented with hierarchically organized visual stimuli that allowed parametrical degrading of the object at the global level. Identification of the global Gestalt was significantly modulated only for the bilateral TPJ stimulation condition. Our results strengthen the view that global Gestalt perception in the human brain involves TPJ and is co-dependent on both hemispheres.
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spelling pubmed-34822422012-10-29 Bilateral Theta-Burst TMS to Influence Global Gestalt Perception Ritzinger, Bernd Huberle, Elisabeth Karnath, Hans-Otto PLoS One Research Article While early and higher visual areas along the ventral visual pathway in the inferotemporal cortex are critical for the recognition of individual objects, the neural representation of human perception of complex global visual scenes remains under debate. Stroke patients with a selective deficit in the perception of a complex global Gestalt with intact recognition of individual objects – a deficit termed simultanagnosia – greatly helped to study this question. Interestingly, simultanagnosia typically results from bilateral lesions of the temporo-parietal junction (TPJ). The present study aimed to verify the relevance of this area for human global Gestalt perception. We applied continuous theta-burst TMS either unilaterally (left or right) or bilateral simultaneously over TPJ. Healthy subjects were presented with hierarchically organized visual stimuli that allowed parametrical degrading of the object at the global level. Identification of the global Gestalt was significantly modulated only for the bilateral TPJ stimulation condition. Our results strengthen the view that global Gestalt perception in the human brain involves TPJ and is co-dependent on both hemispheres. Public Library of Science 2012-10-26 /pmc/articles/PMC3482242/ /pubmed/23110106 http://dx.doi.org/10.1371/journal.pone.0047820 Text en © 2012 Ritzinger et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Ritzinger, Bernd
Huberle, Elisabeth
Karnath, Hans-Otto
Bilateral Theta-Burst TMS to Influence Global Gestalt Perception
title Bilateral Theta-Burst TMS to Influence Global Gestalt Perception
title_full Bilateral Theta-Burst TMS to Influence Global Gestalt Perception
title_fullStr Bilateral Theta-Burst TMS to Influence Global Gestalt Perception
title_full_unstemmed Bilateral Theta-Burst TMS to Influence Global Gestalt Perception
title_short Bilateral Theta-Burst TMS to Influence Global Gestalt Perception
title_sort bilateral theta-burst tms to influence global gestalt perception
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482242/
https://www.ncbi.nlm.nih.gov/pubmed/23110106
http://dx.doi.org/10.1371/journal.pone.0047820
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