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Tetraspanin CD151 plays a key role in skin squamous cell carcinoma
Here we provide the first evidence that tetraspanin CD151 can support de novo carcinogenesis. During two-stage mouse skin chemical carcinogenesis, CD151 reduces tumor lag time and increases incidence, multiplicity, size, and progression to malignant squamous cell carcinoma (SCC), while supporting bo...
Autores principales: | Li, Qinglin, Yang, Xiuwei H., Xu, Fenghui, Sharma, Chandan, Wang, Hong-Xing, Knoblich, Konstantin, Rabinovitz, Isaac, Granter, Scott R., Hemler, Martin E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482293/ https://www.ncbi.nlm.nih.gov/pubmed/22824799 http://dx.doi.org/10.1038/onc.2012.205 |
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