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APPL1 regulates basal NF-κB activity by stabilizing NIK

APPL1 is a multifunctional adaptor protein that binds membrane receptors, signaling proteins and nuclear factors, thereby acting in endosomal trafficking and in different signaling pathways. Here, we uncover a novel role of APPL1 as a positive regulator of transcriptional activity of NF-κB under bas...

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Detalles Bibliográficos
Autores principales:	Hupalowska, Anna, Pyrzynska, Beata, Miaczynska, Marta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482318/ https://www.ncbi.nlm.nih.gov/pubmed/22685329 http://dx.doi.org/10.1242/jcs.105171

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