Cargando…

Antiepileptic drugs for the treatment of neuropathic pain: A systematic review

Many therapies have been proposed for the management of neuropathic pain, and they include the use of different antiepileptic drugs. However, the lack of high quality studies indicates that results on the different neuropathic disorders under study do not recommend a particular drug treatment. This...

Descripción completa

Detalles Bibliográficos
Autores principales: Vargas-Espinosa, Maríam L., Sanmartí-García, Gemma, Vázquez-Delgado, Eduardo, Gay-Escoda, Cosme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482523/
https://www.ncbi.nlm.nih.gov/pubmed/22549682
http://dx.doi.org/10.4317/medoral.18001
_version_ 1782247872240025600
author Vargas-Espinosa, Maríam L.
Sanmartí-García, Gemma
Vázquez-Delgado, Eduardo
Gay-Escoda, Cosme
author_facet Vargas-Espinosa, Maríam L.
Sanmartí-García, Gemma
Vázquez-Delgado, Eduardo
Gay-Escoda, Cosme
author_sort Vargas-Espinosa, Maríam L.
collection PubMed
description Many therapies have been proposed for the management of neuropathic pain, and they include the use of different antiepileptic drugs. However, the lack of high quality studies indicates that results on the different neuropathic disorders under study do not recommend a particular drug treatment. This study makes a systematic review of the published literature on the use of several antiepileptic drugs to treat neuropathic pain, and has the objective of considering both its clinical characteristics and pharmacological use, which will depend on their level of scientific evidence and will follow the principles of evidence-based dentistry. The articles were stratified according to their scientific evidence using the SORT criteria (Strength of Recommendation Taxonomy), and it included those articles that only have level 1 or 2. Randomized clinical trials were stratified according to their level of quality using the JADAD scale, an instrument described by Jadad et al. (7). to assess the quality of clinical trials, while studies with a level below 3 were discarded. Recently, type A or B recommendations are given in favor or against the use of antiepileptic drugs to treat neuropathic pain on the basis of their scientific quality. Key words:Neuropathic pain, antiepileptic drugs (AEDs), trigeminal neuralgia, glossopharyngeal neuralgia, post- herpetic neuralgia, burning mouth syndrome, persistent idiopathic facial pain.
format Online
Article
Text
id pubmed-3482523
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Medicina Oral S.L.
record_format MEDLINE/PubMed
spelling pubmed-34825232012-10-31 Antiepileptic drugs for the treatment of neuropathic pain: A systematic review Vargas-Espinosa, Maríam L. Sanmartí-García, Gemma Vázquez-Delgado, Eduardo Gay-Escoda, Cosme Med Oral Patol Oral Cir Bucal Review-Article Many therapies have been proposed for the management of neuropathic pain, and they include the use of different antiepileptic drugs. However, the lack of high quality studies indicates that results on the different neuropathic disorders under study do not recommend a particular drug treatment. This study makes a systematic review of the published literature on the use of several antiepileptic drugs to treat neuropathic pain, and has the objective of considering both its clinical characteristics and pharmacological use, which will depend on their level of scientific evidence and will follow the principles of evidence-based dentistry. The articles were stratified according to their scientific evidence using the SORT criteria (Strength of Recommendation Taxonomy), and it included those articles that only have level 1 or 2. Randomized clinical trials were stratified according to their level of quality using the JADAD scale, an instrument described by Jadad et al. (7). to assess the quality of clinical trials, while studies with a level below 3 were discarded. Recently, type A or B recommendations are given in favor or against the use of antiepileptic drugs to treat neuropathic pain on the basis of their scientific quality. Key words:Neuropathic pain, antiepileptic drugs (AEDs), trigeminal neuralgia, glossopharyngeal neuralgia, post- herpetic neuralgia, burning mouth syndrome, persistent idiopathic facial pain. Medicina Oral S.L. 2012-09 2012-05-01 /pmc/articles/PMC3482523/ /pubmed/22549682 http://dx.doi.org/10.4317/medoral.18001 Text en Copyright: © 2012 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review-Article
Vargas-Espinosa, Maríam L.
Sanmartí-García, Gemma
Vázquez-Delgado, Eduardo
Gay-Escoda, Cosme
Antiepileptic drugs for the treatment of neuropathic pain: A systematic review
title Antiepileptic drugs for the treatment of neuropathic pain: A systematic review
title_full Antiepileptic drugs for the treatment of neuropathic pain: A systematic review
title_fullStr Antiepileptic drugs for the treatment of neuropathic pain: A systematic review
title_full_unstemmed Antiepileptic drugs for the treatment of neuropathic pain: A systematic review
title_short Antiepileptic drugs for the treatment of neuropathic pain: A systematic review
title_sort antiepileptic drugs for the treatment of neuropathic pain: a systematic review
topic Review-Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482523/
https://www.ncbi.nlm.nih.gov/pubmed/22549682
http://dx.doi.org/10.4317/medoral.18001
work_keys_str_mv AT vargasespinosamariaml antiepilepticdrugsforthetreatmentofneuropathicpainasystematicreview
AT sanmartigarciagemma antiepilepticdrugsforthetreatmentofneuropathicpainasystematicreview
AT vazquezdelgadoeduardo antiepilepticdrugsforthetreatmentofneuropathicpainasystematicreview
AT gayescodacosme antiepilepticdrugsforthetreatmentofneuropathicpainasystematicreview