Cargando…
Antiepileptic drugs for the treatment of neuropathic pain: A systematic review
Many therapies have been proposed for the management of neuropathic pain, and they include the use of different antiepileptic drugs. However, the lack of high quality studies indicates that results on the different neuropathic disorders under study do not recommend a particular drug treatment. This...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medicina Oral S.L.
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482523/ https://www.ncbi.nlm.nih.gov/pubmed/22549682 http://dx.doi.org/10.4317/medoral.18001 |
_version_ | 1782247872240025600 |
---|---|
author | Vargas-Espinosa, Maríam L. Sanmartí-García, Gemma Vázquez-Delgado, Eduardo Gay-Escoda, Cosme |
author_facet | Vargas-Espinosa, Maríam L. Sanmartí-García, Gemma Vázquez-Delgado, Eduardo Gay-Escoda, Cosme |
author_sort | Vargas-Espinosa, Maríam L. |
collection | PubMed |
description | Many therapies have been proposed for the management of neuropathic pain, and they include the use of different antiepileptic drugs. However, the lack of high quality studies indicates that results on the different neuropathic disorders under study do not recommend a particular drug treatment. This study makes a systematic review of the published literature on the use of several antiepileptic drugs to treat neuropathic pain, and has the objective of considering both its clinical characteristics and pharmacological use, which will depend on their level of scientific evidence and will follow the principles of evidence-based dentistry. The articles were stratified according to their scientific evidence using the SORT criteria (Strength of Recommendation Taxonomy), and it included those articles that only have level 1 or 2. Randomized clinical trials were stratified according to their level of quality using the JADAD scale, an instrument described by Jadad et al. (7). to assess the quality of clinical trials, while studies with a level below 3 were discarded. Recently, type A or B recommendations are given in favor or against the use of antiepileptic drugs to treat neuropathic pain on the basis of their scientific quality. Key words:Neuropathic pain, antiepileptic drugs (AEDs), trigeminal neuralgia, glossopharyngeal neuralgia, post- herpetic neuralgia, burning mouth syndrome, persistent idiopathic facial pain. |
format | Online Article Text |
id | pubmed-3482523 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medicina Oral S.L. |
record_format | MEDLINE/PubMed |
spelling | pubmed-34825232012-10-31 Antiepileptic drugs for the treatment of neuropathic pain: A systematic review Vargas-Espinosa, Maríam L. Sanmartí-García, Gemma Vázquez-Delgado, Eduardo Gay-Escoda, Cosme Med Oral Patol Oral Cir Bucal Review-Article Many therapies have been proposed for the management of neuropathic pain, and they include the use of different antiepileptic drugs. However, the lack of high quality studies indicates that results on the different neuropathic disorders under study do not recommend a particular drug treatment. This study makes a systematic review of the published literature on the use of several antiepileptic drugs to treat neuropathic pain, and has the objective of considering both its clinical characteristics and pharmacological use, which will depend on their level of scientific evidence and will follow the principles of evidence-based dentistry. The articles were stratified according to their scientific evidence using the SORT criteria (Strength of Recommendation Taxonomy), and it included those articles that only have level 1 or 2. Randomized clinical trials were stratified according to their level of quality using the JADAD scale, an instrument described by Jadad et al. (7). to assess the quality of clinical trials, while studies with a level below 3 were discarded. Recently, type A or B recommendations are given in favor or against the use of antiepileptic drugs to treat neuropathic pain on the basis of their scientific quality. Key words:Neuropathic pain, antiepileptic drugs (AEDs), trigeminal neuralgia, glossopharyngeal neuralgia, post- herpetic neuralgia, burning mouth syndrome, persistent idiopathic facial pain. Medicina Oral S.L. 2012-09 2012-05-01 /pmc/articles/PMC3482523/ /pubmed/22549682 http://dx.doi.org/10.4317/medoral.18001 Text en Copyright: © 2012 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review-Article Vargas-Espinosa, Maríam L. Sanmartí-García, Gemma Vázquez-Delgado, Eduardo Gay-Escoda, Cosme Antiepileptic drugs for the treatment of neuropathic pain: A systematic review |
title | Antiepileptic drugs for the treatment of neuropathic pain:
A systematic review |
title_full | Antiepileptic drugs for the treatment of neuropathic pain:
A systematic review |
title_fullStr | Antiepileptic drugs for the treatment of neuropathic pain:
A systematic review |
title_full_unstemmed | Antiepileptic drugs for the treatment of neuropathic pain:
A systematic review |
title_short | Antiepileptic drugs for the treatment of neuropathic pain:
A systematic review |
title_sort | antiepileptic drugs for the treatment of neuropathic pain:
a systematic review |
topic | Review-Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482523/ https://www.ncbi.nlm.nih.gov/pubmed/22549682 http://dx.doi.org/10.4317/medoral.18001 |
work_keys_str_mv | AT vargasespinosamariaml antiepilepticdrugsforthetreatmentofneuropathicpainasystematicreview AT sanmartigarciagemma antiepilepticdrugsforthetreatmentofneuropathicpainasystematicreview AT vazquezdelgadoeduardo antiepilepticdrugsforthetreatmentofneuropathicpainasystematicreview AT gayescodacosme antiepilepticdrugsforthetreatmentofneuropathicpainasystematicreview |