Sequence specific detection of bacterial 23S ribosomal RNA by TLR13

Toll-like receptors (TLRs) detect microbial infections and trigger innate immune responses. Among vertebrate TLRs, the role of TLR13 and its ligand are unknown. Here we show that TLR13 detects the 23S ribosomal RNA of both gram-positive and gram-negative bacteria. A sequence containing 13 nucleotide...

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Detalles Bibliográficos
Autores principales: Li, Xiao-Dong, Chen, Zhijian J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2012
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482692/
https://www.ncbi.nlm.nih.gov/pubmed/23110254
http://dx.doi.org/10.7554/eLife.00102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482692/
https://www.ncbi.nlm.nih.gov/pubmed/23110254
http://dx.doi.org/10.7554/eLife.00102

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