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Solid-state characterization of lacidipine/PVP K(29/32) solid dispersion primed by solvent co-evaporation
BACKGROUND: Lacidipine (LCDP) is a 1,4-dihydropyridine derivative categorized as an anti-hypertensive Ca2+ channel blocker having very low solubility, and thus very low oral bioavailability, which presents a challenge to the formulation scientists. Homogeneous distribution of poorly water-soluble dr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482771/ https://www.ncbi.nlm.nih.gov/pubmed/23119238 http://dx.doi.org/10.4103/2230-973X.100048 |