Non-randomized mtDNA damage after ionizing radiation via charge transport

Although it is well known that there are mutation hot spots in mtDNA, whether there are damage hot spots remain elusive. In this study, the regional DNA damage of mitochondrial genome after ionizing radiation was determined by real-time quantitative PCR. The mtDNA damage level was found to be dose-d...

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Detalles Bibliográficos
Autores principales: Zhou, Xin, Liu, Xinguo, Zhang, Xin, Zhou, Rong, He, Yang, Li, Qiang, Wang, Zhenhua, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483021/
https://www.ncbi.nlm.nih.gov/pubmed/23110249
http://dx.doi.org/10.1038/srep00780

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