NADPH Oxidase 4 Mediates Insulin-Stimulated HIF-1α and VEGF Expression, and Angiogenesis In Vitro

Acute intensive insulin therapy causes a transient worsening of diabetic retinopathy in type 1 diabetes patients and is related to VEGF expression. Reactive oxygen species (ROS) have been shown to be involved in HIF-1α and VEGF expression induced by insulin, but the role of specific ROS sources has...

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Detalles Bibliográficos
Autores principales: Meng, Dan, Mei, Aihong, Liu, Junxu, Kang, Xueling, Shi, Xianglin, Qian, Ruizhe, Chen, Sifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483150/
https://www.ncbi.nlm.nih.gov/pubmed/23144758
http://dx.doi.org/10.1371/journal.pone.0048393

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