Protective Antibody and CD8(+) T-Cell Responses to the Plasmodium falciparum Circumsporozoite Protein Induced by a Nanoparticle Vaccine

BACKGROUND: The worldwide burden of malaria remains a major public health problem due, in part, to the lack of an effective vaccine against the Plasmodium falciparum parasite. An effective vaccine will most likely require the induction of antigen specific CD8(+) and CD4(+) T-cells as well as long-la...

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Detalles Bibliográficos
Autores principales: Kaba, Stephen A., McCoy, Margaret E., Doll, Tais A. P. F., Brando, Clara, Guo, Qin, Dasgupta, Debleena, Yang, Yongkun, Mittelholzer, Christian, Spaccapelo, Roberta, Crisanti, Andrea, Burkhard, Peter, Lanar, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483151/
https://www.ncbi.nlm.nih.gov/pubmed/23144750
http://dx.doi.org/10.1371/journal.pone.0048304

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