Over-Expression of DSCR1 Protects against Post-Ischemic Neuronal Injury

BACKGROUND AND PURPOSE: The Down syndrome candidate region 1 (DSCR1) gene is located on human chromosome 21 and its protein is over-expressed in brains of Down syndrome individuals. DSCR1 can modulate the activity of calcineurin, a phosphatase abundant in the brain, but its influence on stroke outco...

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Detalles Bibliográficos
Autores principales: Brait, Vanessa H., Martin, Katherine R., Corlett, Alicia, Broughton, Brad R. S., Kim, Hyun Ah, Thundyil, John, Drummond, Grant R., Arumugam, Thiruma V., Pritchard, Melanie A., Sobey, Christopher G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483156/
https://www.ncbi.nlm.nih.gov/pubmed/23144708
http://dx.doi.org/10.1371/journal.pone.0047841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483156/
https://www.ncbi.nlm.nih.gov/pubmed/23144708
http://dx.doi.org/10.1371/journal.pone.0047841

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