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Over-Expression of DSCR1 Protects against Post-Ischemic Neuronal Injury
BACKGROUND AND PURPOSE: The Down syndrome candidate region 1 (DSCR1) gene is located on human chromosome 21 and its protein is over-expressed in brains of Down syndrome individuals. DSCR1 can modulate the activity of calcineurin, a phosphatase abundant in the brain, but its influence on stroke outco...
Autores principales: | Brait, Vanessa H., Martin, Katherine R., Corlett, Alicia, Broughton, Brad R. S., Kim, Hyun Ah, Thundyil, John, Drummond, Grant R., Arumugam, Thiruma V., Pritchard, Melanie A., Sobey, Christopher G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483156/ https://www.ncbi.nlm.nih.gov/pubmed/23144708 http://dx.doi.org/10.1371/journal.pone.0047841 |
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