Secondhand smoke in combination with ambient air pollution exposure is associated with increasedx CpG methylation and decreased expression of IFN-γ in T effector cells and Foxp3 in T regulatory cells in children

BACKGROUND: Secondhand smoke (SHS) and ambient air pollution (AAP) exposures have been associated with increased prevalence and severity of asthma and DNA modifications of immune cells. In the current study, we examined the association between SHS and AAP with DNA methylation and expression of inter...

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Detalles Bibliográficos
Autores principales: Kohli, Arunima, Garcia, Marco A, Miller, Rachel L, Maher, Christina, Humblet, Olivier, Hammond, S Katharine, Nadeau, Kari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483214/
https://www.ncbi.nlm.nih.gov/pubmed/23009259
http://dx.doi.org/10.1186/1868-7083-4-17

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